Acta Medica International

ORIGINAL ARTICLE
Year
: 2022  |  Volume : 9  |  Issue : 1  |  Page : 6--9

Brain and COVID: A case series of neurovascular complications


Rajagopal Srinath1, Subrat Kumar Nanda2, Vikram Asturkar2, FMH Ahmad2, Vinny Wilson1, Uday Yanamandra1, Anil Menon1 
1 Department of Internal Medicine, AFMC, Pune, Maharashtra, India
2 Department of Neurology, Command Hospital (SC), Pune, Maharashtra, India

Correspondence Address:
Dr. Rajagopal Srinath
Department of Internal Medicine, AFMC, Pune, Maharashtra
India

Introduction: COVID-19 is caused due to infection with severe acute respiratory syndrome-coronavirus-2. A change in the epidemiological pattern of neurovascular diseases has been observed among patients who have had COVID-19 infection. There are not enough studies which have evaluated the neurovascular manifestations among patients of COVID-19 infection. Materials and Methods: This single-center observational study was intended to evaluate the correlation between various COVID-19-related parameters with the outcomes of vascular events among patients of COVID-19 who developed neurovascular complications. The study was conducted at a tertiary hospital in Pune, India, from February 01, 2021, to October 10, 2021. The study population involved patients with COVID-19 of varying severity and associated neurovascular complications. The total number of patients was 22 in number. The deidentified data were analyzed using JMP version 10.040. Results: Among a total of 22 patients, 16 (73%) had arterial infarcts, 5 (23%) had venous infarcts, whereas 1 (4%) had intracerebral hemorrhage. Four (18%) patients had features of severe COVID-19 and 2 (9%) of them had a modified Rankin Scale of six. There was a strong correlation between the severity of COVID infection and the severity of neurovascular complications. A positive correlation was observed between the time duration from Reverse transcriptase polymerase chain reaction (RT-PCR) positivity to neurovascular complications with the duration of >45 days having a poorer outcome. Conclusion: COVID-19 is more likely to cause thrombotic vascular events including stroke. The severity of COVID-19 is directly correlated with poorer outcomes. The duration between RT-PCR positivity and neurovascular symptoms if >45 days, has a poorer outcome.


How to cite this article:
Srinath R, Nanda SK, Asturkar V, Ahmad F, Wilson V, Yanamandra U, Menon A. Brain and COVID: A case series of neurovascular complications.Acta Med Int 2022;9:6-9


How to cite this URL:
Srinath R, Nanda SK, Asturkar V, Ahmad F, Wilson V, Yanamandra U, Menon A. Brain and COVID: A case series of neurovascular complications. Acta Med Int [serial online] 2022 [cited 2022 Aug 19 ];9:6-9
Available from: https://www.actamedicainternational.com/article.asp?issn=2349-0578;year=2022;volume=9;issue=1;spage=6;epage=9;aulast=Srinath;type=0