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Year : 2021  |  Volume : 8  |  Issue : 2  |  Page : 163-165

Cytological grading of prostate carcinoma: A comparative study with the international society of urologic pathology grading system

1 Department of Pathology, GSVM Medical College, Kanpur, Uttar Pradesh, India
2 Department of Biochemistry, LPS Institute of Cardiology, Kanpur, Uttar Pradesh, India
3 Department of Surgery, GSVM Medical College, Kanpur, Uttar Pradesh, India

Correspondence Address:
Dr. Chayanika Kala
L-21 GSVM Medical College Campus, Kanpur - 208 002, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/amit.amit_148_21

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Introduction: The Gleason grading system is one of the most powerful prognostic predictors of carcinoma prostate. In 2014, a newer grading system, the International Society of Urologic Pathology (ISUP) grading system was proposed. The present study is a retrospective study conducted to compare the cytological grading of prostate carcinoma with the newly proposed ISUP grading system for prostate carcinoma. Materials and Methods: The present study is a retrospective study that included 42 cases of carcinoma prostate. The clinical data of the cases, fine-needle aspiration cytology slides, and histological slides were retrieved and reviewed. The cases were regraded using the ISUP grading system for prostate carcinoma. Statistical analysis was done using the Statistical Package for the Social Sciences (SPSS). Data were statistically analyzed and Chi-square testing was used to compare the two grading systems. Results: A total of 42 cases were studied. The preoperative grade was assigned to the smears and 26.19% (11 cases) were categorized as grade 1, 40.47% (17 cases) as grade 2, and 33.3% (14 cases) as grade 3. Histological sections were also graded according to the ISUP/grade groups (GG) system and 26.19% (11 cases) were graded as GG 1, 33.3% (14 cases) as GG2, 19.04% (8 cases) as GG3, 16.67% (7 cases) as GG4, and 4.47% (2 cases) as GG5. Conclusion: In the present study, it was concluded that there is a direct concordance between the histologic grade as proposed in the ISUP grading system and the cytologic grade on FNA.

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