ORIGINAL ARTICLE |
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Year : 2016 | Volume
: 3
| Issue : 2 | Page : 24-26 |
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Developmental disorders-genetic view
Suruchi Jamkhedkar
Department of Life Sciences University of Mumbai, Vidyanagari Campus, Santacruz (E), Mumbai-400 098, India
Correspondence Address:
Suruchi Jamkhedkar Department of Life Sciences University of Mumbai, Vidyanagari Campus, Santacruz (E), Mumbai-400 098 India
 Source of Support: None, Conflict of Interest: None
DOI: 10.5530/ami.2016.2.6
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Objective: To review genetic cause of developmental disorders.
Methodology: A survey consisting of 70 children with developmental disorder was done for genetic evaluation of these disorders through case history and interview of the parents.
Results: The cause was found to be combination of genetic variation with environmental risks due to which epigenetic changes might have taken place in prenatal stages in 81% of the cases in the survey. Only 16% of cases showed mendelian inheritance.
Conclusion: The results indicate that developmental disorders are of epigenetical nature rather than mendelian inheritance.
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