Cardiovascular Reactivity in young adults with hypertensive and normotensive parents: A Gender based Comparative Study

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Acta Medica International,2017,4,1,101-109.
Published:January 2017
Type:Original Article

Cardiovascular Reactivity in young adults with hypertensive and normotensive parents: A Gender based Comparative Study

Anjali Verma1, Shishir Ranjan Arora2, Manoj Kumar3

1Department of Physiology, TMMC & RC, Moradabad, Uttar Pradesh, INDIA.

2Department of Physiology, Muzaffarnager Medical college, Muzaffarnager Uttar Pradesh, INDIA.

3Department of Physiology, TMMC & RC, Moradabad, Uttar Pradesh, INDIA.

Abstract:

Introduction: Essential hypertension begins due to mutation of specific genes that contribute to the risk of developing hypertension. Genetic contribution was recognized 25 years ago, now formulated from time to time. Some studies have also proven that the hypertension in father had strong contribution in their individual than mother. The aim of the study is to compare the cardiovascular reactivity in male and female subjects with hypertensive and normotensive parents. Materials and methods: This comparative study was conducted in physiology department of Teerthanker Mahaveer medical college and research center, Moradabad. The research work was initiated after taken the ethical clearance from the ethical committee of the college. Three different stressors: cold pressor task, cycling and videogame were used. Total 120 subjects were taken for the study in which 77 were male and 43 were female. Result: Male subjects of normotensive parents had slightly higher HR rate (mean: 76.73/min) compared to the female subjects (mean: 75/min) with p value >0.05. Female subjects of hypertensive parents had higher HR rate (mean: 82.72/min) compared to the male subjects (mean: 73.95/min) with p value < 0.001. Conclusion: Male subjects with normotensive parents had higher resting HR, SBP &DBP than Female subjects with normotensive parents, but the difference was significant only in SBP. Female subjects with hypertensive parents group was showing higher resting HR than male subjects with hypertensive parents group, remains higher after stress also with insignificant difference. Thus, subjects with hypertensive parents showing increased CVR to stress are more likely to develop future hypertension, and the risk is greater for male subjects.

Comparison of Basal Parameters in Male and Female subjects of Normotensive Parents