Thalassemia: Genetically Transmitted Blood Disorder

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Acta Medica International,2015,2,2,195.
Published:July 2015
Type:Short Communication

Thalassemia: Genetically Transmitted Blood Disorder

Kausar Rehman Khan

MSc. Genetics M Phil MBA, R-23 Hina Bungalows, Behind Askari 4, Block 19, Gulistan-e-Jauhar, Karachi, Pakistan


Alpha Thalassemia is most common Inherited Blood Disorder in the Asian/Pacific Islander population. Beta Thalassemia is common in the Mediterranean population.Autosomal recessive in Inheritance pattern. Thalassemia ia a blood disorder passed down through families (inherited) in which the body makes an abnormal form of heamoglobin. The deficient synthesis of one or more of the normal blood globin chains.Blood disorder ranging from minor to severe.The disorder results in excessive destruction of red blood cells leading to Anemia.Alph Thalaseemia occurs when a mutation in the genethat codes for alpha globin results in reduced or absent production of alpha globin.Beta Thalassemia occurs with a corresponding change in beta globin genes. Read more......