WHO Recommended Tools to Improve Diagnosis of Active and Drug Resistant Tuberculosis

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Acta Medica International,2015,2,2,118-129.
Published:July 2015
Type:Review Article

WHO Recommended Tools to Improve Diagnosis of Active and Drug Resistant Tuberculosis

Shubhada Shenai
 

1Center for Emerging Pathogens, Department of Medicine, New Jersey Medical School - Rutgers University, Newark, New Jersey, USA

Abstract:

The successful arrest or cure of tuberculosis (TB) depends largely on early case detection and proper treatment. Currently, several promising diagnostic tools with improved sensitivity and speed are available. Old microscopic and culture based technologies have been revisited and new molecular technologies have been developed. In recent years, World Health Organization (WHO) evaluated and endorsed different TB diagnostic tools and published various policy statements. These policy statements address improvements in smear microscopy, use of commercial and non commercial culture based techniques and rapid molecular assays. This is the first comprehensive review compiling pros and cons of WHO recommended TB diagnostic tools for effective implementation in TB endemic regions.

Global Incidence of Tuberculosis. (Adapted from Reference 1). (a) shows the estimated global incidence of tuberculosis is 2013. Source: WHO report 2014, (b) shows estimated absolute numbers of TB cases and deaths (in millions per year), 1990-2013