Signet-ring Gastric Carcinoma, at Bahrain

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Acta Medica International,2016,3,1,210-213.
Published:January 2016
Type:Case Report

Signet-ring Gastric Carcinoma, at Bahrain

Amal Almahroos1, Khalid A. Al-Sindi2, Mandeep Bedi3, Maitham Alsadadi4, Mohamed A. Alhamar5, Mulazim Hussain Bukhari6

1SHO, University Medical Center, King Abdulla Medical City, Kingdom of Bahrain,

2Prof of Pathology, King Hamad University Hospital, Bahrain,

3Pathologist, Kolkata Police Hospitals,Kolkata, India,

4Consultant gastroenterologist, University Medical Center, King Abdulla Medical City, Kingdom of Bahrain,

5Senior House officer, Histopathology, King Hamad University Hospital, Building 2345, Road 2835, Block 228, Busaiteen, Kingdom of Bahrain,

6Prof of Pathology, Punjab Medical University, Faisal Abad, Pakistan

Abstract:

Signet ringcarcinoma (SRC), a variant of gastric adenocarcinoma, is known to have a poor prognosis, especially when arising in the young population. In this report, two cases of gastric SRC carcinomas with different outcomes are described. The first case is a 49 years old Bahraini lady who presented with abdominal pain and was found to have a gastric ulcerover the lesser curvature on endoscopy and her biopsy showed features ofa poorly differentiated signet ring adenocarcinoma. This patient was managed by a timelysubtotal gastrectomy with adjuvant chemoradiotherapy. The second caseis ofa 34 years old Bahraini male whom presented withmild dyspepsia and in whomSRCwas an incidental finding on initial endoscopic biopsy that was later confirmed by targeted biopsy.This patientwas advised total gastrectomybut died due to delay in appropriate and timely interventions primarily due to his multiple consultations regarding the same matter.

Lesser curvature fundal gastric ulcer