Cystatin C: An Early Marker of Cardiac Complications in Diabetics

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Acta Medica International,2015,2,1,84-86.
Published:January 2015
Type:Original Article

Cystatin C: An Early Marker of Cardiac Complications in Diabetics

Kiran Bhat1, Ashok K. Lal2, Sohaib Ahmad3, Monica Kakkar4
1Assistant Professor, Department of Biochemistry, SGRRIMHS, Patel Nagar, Dehradun, Uttarakhand, India, 2Professor, Department of Biochemistry, HIHT, Dehradun, Uttarakhand, India,

3Professor, Department of Medicine, HIHT, Dehradun, Uttarakhand, India,
4Associate Professor, Department of Biochemistry, HIHT, Dehradun, India

Abstract:

Introduction: Cardiovascular disease is one of the common complications of Diabetes mellitus. Serum Cystatin C level has been suggested as a marker for cardiac complications in diabetes. Material and Methods: We studied serum Cystatin C level in Diabetics to fi nd if correlation exists between cardiac complications and elevated Cystatin C levels. Results: A total of 50 diabetics were studied out of whom 25 had cardiac complications and the rest did not have cardiac complications. No significant difference was observed between Serum Cystatin C levels of diabetics with cardiac complications (mean 1∙5±0∙45) and diabetics without cardiac complications (1∙4±0∙46) although Cystatin C levels were found to be elevated in diabetic cases. Conclusion: Keeping in view the
significant difference (p=0∙000) in Cystatin C levels of healthy and diabetic patients, it is reasonable to accept the importance of Cystatin C as an indicator of diabetes and its associated complications.